Virazole / Copegus / Rebetol

Ribavirin (Virazole, Copegus, Rebetol) is a broad-spectrum nucleoside antiviral used off-label and per WHO guidance for viral haemorrhagic fevers such as Lassa fever, alongside its established roles in hepatitis C and RSV.

Strength: 200 mg

Pack Size: Bottle / blister (tablets)

Storage: Below 30°C

Form: Tablet / Capsule

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Ribavirin is a synthetic guanosine nucleoside analogue with broad-spectrum activity against many RNA and some DNA viruses. Marketed under brand names including Virazole, Copegus and Rebetol, it interferes with viral RNA and protein synthesis through several mechanisms.
For Lassa fever, ribavirin is recommended by the WHO and used off-label as the principal antiviral option, with greatest benefit when started early in the course of illness. It is also established for chronic hepatitis C (in combination regimens) and, as an aerosol, for severe RSV infection.
Oral ribavirin is supplied as tablets or capsules across its brands, while intravenous and aerosolised forms exist for specific indications. Treatment requires monitoring because ribavirin can cause haemolytic anaemia and is contraindicated in pregnancy.
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