TM Owner Bristol Myers Squibb
Reyataz 300mg Capsule
Global Shipping : Reliable Global Distribution Network
Express Delivery : Priority Shipping for Every Order
Secure Payments : Trusted Payment Protection System
Disclaimer
Secure Handling
24/7 Worldwide Support
Global Access
Worldwide Access to Health
Cold-Chain Expert
Excellence in Cold-Chain
Trusted Supply
Certified Medical Supply
Indications & Clinical Uses
- Reyataz 300mg capsules contain atazanavir, a protease inhibitor antiretroviral.
- It is approved for the treatment of HIV-1 infection in adults and paediatric patients 3 months and older weighing at least 5kg, always combined with other antiretroviral medicines as part of a full HIV regimen - Reyataz is never used alone.
- The 300mg strength is typically given once daily together with a low dose of a boosting agent (such as ritonavir or cobicistat) to increase and maintain atazanavir blood levels; unboosted regimens use different dosing and are used less often today.
- Reyataz does not cure HIV infection or prevent its transmission to others, and patients remain at risk of HIV-related illnesses while taking it.
- It is taken by mouth, usually with food, and self-administered at home as part of long-term daily treatment, with regular blood tests to monitor the virus and liver function.
Side Effects
- Reyataz has no boxed warning.
- The most common side effects are nausea, headache, abdominal pain, vomiting, diarrhoea, insomnia, dizziness and rash.
- A distinctive effect is asymptomatic hyperbilirubinaemia - a harmless rise in bilirubin that can cause yellowing of the skin or eyes (jaundice) in more than 1 in 10 patients; this reverses when the medicine is stopped and does not usually require dose reduction, but tell your provider if it troubles you.
- Serious skin reactions, including Stevens-Johnson syndrome, have been reported rarely - stop Reyataz and seek urgent care for blistering, peeling skin or a widespread rash with fever.
- Reyataz can also cause new or worsening diabetes, changes in body fat distribution, and immune reconstitution inflammatory syndrome as the immune system recovers.
- Report chest pain, fainting or an irregular heartbeat promptly, since atazanavir can affect the heart's electrical conduction.
Precautions & Warnings
- Reyataz can prolong the PR interval of the heart's electrical conduction, so it should be used cautiously, with ECG monitoring, in patients with existing conduction abnormalities or taking other PR-prolonging medicines.
- It is not recommended in severe liver impairment, and dose adjustment or extra monitoring is needed in moderate impairment or in chronic hepatitis B or C co-infection; liver function tests are checked periodically, especially early in treatment.
- Kidney stones and gallbladder-related events have been reported.
- Reyataz should not be started or continued without its boosting agent unless directed, and never combined with medicines it is contraindicated with.
- Discuss pregnancy plans with your provider: atazanavir passes into breast milk and HIV can be transmitted through breastfeeding, so feeding method should be planned with your care team.
- Genotypic resistance testing helps guide whether Reyataz is a suitable choice for you.
Avoid Interactions
- Reyataz must not be combined with rifampin, alfuzosin, certain ergot derivatives, oral midazolam, triazolam, lurasidone, ranolazine, the herbal supplement St John's wort, or simvastatin/lovastatin at standard doses, since these combinations can cause serious or life-threatening reactions or make Reyataz ineffective.
- Proton pump inhibitors and H2-blockers significantly reduce atazanavir absorption and require specific dose timing or avoidance - discuss any indigestion or reflux medicine with your provider before use.
- Other strong enzyme inducers or inhibitors, including certain seizure medicines and some hormonal contraceptives, can also change atazanavir levels.
- Reyataz interacts with many other antiretrovirals, so your combination regimen is chosen carefully by your HIV specialist.
- Tell your prescriber and pharmacist about every prescription, over-the-counter medicine, herbal product and supplement you take before starting or changing Reyataz.
References
Frequently Asked Questions
Reyataz (atazanavir) is a protease inhibitor used to treat HIV-1 infection in adults and children 3 months and older weighing at least 5kg. It is always combined with other antiretroviral medicines and a low-dose booster as part of a complete HIV treatment regimen.
Reyataz 300mg capsules are usually taken once daily by mouth with food, together with a booster (ritonavir or cobicistat) and other antiretroviral medicines. Take it at the same time each day, since missed or irregular doses can let the virus become resistant.
Reyataz commonly causes nausea, headache, abdominal pain and rash. It often raises bilirubin, which can turn the skin or eyes yellow (jaundice) but usually needs no treatment change. Rarely, it causes severe skin reactions - seek urgent care for blistering or peeling skin.
Avoid rifampin, St John's wort, simvastatin, lovastatin and certain other medicines that are contraindicated with atazanavir. Proton pump inhibitors reduce Reyataz absorption, so timing or avoidance is needed. Tell your prescriber about every medicine, herbal product and supplement you take.
Your provider checks liver function tests periodically, since Reyataz commonly raises bilirubin and can affect the liver, and may check an ECG if you have a heart conduction problem. Routine HIV viral load and CD4 count monitoring continue as part of standard HIV care.
Discuss pregnancy plans with your HIV specialist before starting or continuing Reyataz, since regimen choice can change during pregnancy. Atazanavir passes into breast milk, and HIV can be transmitted through breastfeeding, so your care team will help you plan the safest feeding method.
Trusted & Reliable – Your Partner in Global Distribution.
We provide comprehensive lines of pharmaceutical products to support all your healthcare distribution needs.
