Betaferon / Betaseron
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Interferon beta-1b, marketed as Betaferon and Betaseron, is a recombinant form of a naturally occurring interferon with immunomodulatory and antiviral properties. It is an established disease-modifying therapy for relapsing forms of multiple sclerosis.
Because interferons interfere with viral replication and modulate immune responses, interferon beta-1b has been investigated as a component of antiviral regimens for coronavirus infections, including Middle East respiratory syndrome (MERS), often in combination with other agents. This use remains investigational and is not an approved indication.
It is supplied as a lyophilised powder for subcutaneous injection after reconstitution, given on an alternate-day schedule in its approved MS indication. Treatment is associated with flu-like symptoms and injection-site reactions.
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