Avigan

Avigan, the brand name for favipiravir, is an oral antiviral originally developed by Toyama Chemical (a Fujifilm group company) and approved in Japan for novel or re-emerging pandemic influenza. It acts as a selective inhibitor of viral RNA-dependent RNA polymerase, blocking replication of a broad range of RNA viruses.
Because of this broad-spectrum mechanism, favipiravir has been studied investigationally against filoviruses including Marburg and Ebola, as well as Lassa and other haemorrhagic fever viruses, although it is not an approved therapy for these indications. Its oral tablet formulation makes it attractive for field and outbreak settings.
Favipiravir is a prodrug that is converted intracellularly to its active triphosphate form. Use against Marburg remains investigational and should follow current research protocols and specialist guidance.
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