TM Owner Bausch & Lomb
Muro 128 5% Eye Drops
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Indications & Clinical Uses
- Muro 128 5% is an over-the-counter ophthalmic solution containing sodium chloride 5%, a hypertonicity (osmotic) agent, manufactured by Bausch & Lomb.
- It is used for the temporary relief of corneal edema, a swelling of the eye's clear front surface that can cause blurred vision, halos around lights and eye discomfort, most often from corneal dystrophy or after eye surgery.
- Muro 128 draws excess fluid out of the swollen cornea by osmosis, easing the associated symptoms; it does not treat the underlying cause of the swelling.
- It is available without a prescription in the US and can be used in adults and, under medical guidance, in children with eye conditions causing corneal swelling.
- It is intended only as an eye drop for topical ophthalmic use and must never be swallowed, injected, or applied to the ear or anywhere other than the eye.
Side Effects
- The most common effect of Muro 128 5% eye drops is temporary stinging or burning in the eye immediately after each dose, which usually settles within a few minutes.
- Some people notice mild eye irritation, redness or watering, especially when treatment is first started.
- Brief blurring of vision can occur right after instillation because of the drop itself rather than worsening of the underlying corneal swelling.
- Serious reactions are uncommon, but stop using Muro 128 and seek medical advice promptly if you develop eye pain, a change in vision that does not clear, ongoing redness, worsening swelling, or signs of an allergic reaction such as eyelid swelling or a rash around the eye.
- If symptoms of corneal edema do not improve, or get worse, within 72 hours of regular use, stop the drops and contact an eye care provider, since this may indicate a condition needing different treatment.
Precautions & Warnings
- Muro 128 5% is for topical ophthalmic use in the eye only; it must never be injected, swallowed or used in the ear.
- Remove contact lenses before use, and wait until any accompanying eye irritation has resolved before reinserting them, since eye drops like this are not recommended for use with lenses in place.
- To avoid contaminating the solution, do not let the dropper tip touch the eye, eyelid, fingers or any other surface, and keep the container tightly closed between uses.
- Consult a healthcare provider before use if you have eye pain, are already using other eye medicines, or if symptoms of corneal edema do not improve within 72 hours, since these can signal a condition needing prescription treatment.
- There are no specific pregnancy, breastfeeding or driving warnings on the label, but anyone with pre-existing eye disease, particularly children, should use Muro 128 only under the direction of a doctor or eye care professional.
Avoid Interactions
- No specific drug-interaction studies are described in the Muro 128 5% label, and the manufacturer does not list interactions with oral or systemic medicines.
- As a general precaution, if you use other eye drops or ophthalmic ointments, space them roughly 5 to 10 minutes apart from Muro 128 so that one product does not wash out another, applying any ointment last if you use both a drop and an ointment.
- Tell a healthcare provider or pharmacist about all other eye medicines, contact lens solutions and systemic drugs you use, particularly if you have glaucoma or another eye condition being treated with prescription drops, so they can confirm Muro 128 will not interfere with your other treatment.
- Do not mix Muro 128 with any other liquid before use, and discard the solution if it becomes discoloured or contaminated, since diluting or combining products can change its intended hypertonic effect.
References
Frequently Asked Questions
Muro 128 is an over-the-counter eye drop containing sodium chloride 5%, used for temporary relief of corneal edema, a swelling of the eye's clear front surface that can blur vision or cause halos around lights. It draws excess fluid out of the cornea but does not treat the underlying cause.
Instill 1 or 2 drops of Muro 128 into the affected eye every 3 to 4 hours, or as directed by your eye doctor. Remove contact lenses first, avoid touching the dropper tip to the eye, and keep the container tightly closed between uses.
Muro 128 commonly causes brief stinging or burning right after each drop, and sometimes mild redness or watering. These usually settle within minutes. Stop use and see a doctor if you get eye pain, vision changes, or redness that doesn't improve.
Avoid wearing contact lenses while your eye is irritated, and don't let the dropper tip touch your eye, eyelid or any surface, to prevent contamination. Muro 128 has no known systemic drug interactions, but space other eye drops a few minutes apart from it.
Store Muro 128 upright at 15°C to 25°C, away from heat and light, and keep it from freezing. Stop using it and contact a healthcare provider if corneal edema symptoms do not improve, or get worse, within 72 hours of regular use.
Muro 128 can be used in children, but the dose and suitability should be confirmed by a doctor first, since paediatric dosing isn't fixed on the label. There's no specific pregnancy or driving warning, but anyone with eye disease should use it under medical guidance.

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