TM Owner AstraZeneca
Tudorza Pressair 400mcg Inhaler
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Indications & Clinical Uses
- Tudorza Pressair (aclidinium bromide) is a long-acting anticholinergic bronchodilator used for maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults.
- It is not intended for acute bronchospasm relief.
- The medication helps improve lung function and reduce airway obstruction by relaxing airway smooth muscles.
Side Effects
- Common side effects of Tudorza Pressair include headache (occurring in about 7% of patients), nasopharyngitis (upper respiratory inflammation in about 6%), and cough (in about 3%).
- Other less frequent effects include diarrhea, sinusitis, and rhinitis.
- Patients should seek urgent help if they experience paradoxical bronchospasm, severe eye pain, difficulty urinating, or signs of hypersensitivity reactions.
Precautions & Warnings
- Tudorza Pressair is not suitable for acute bronchospasm treatment.
- Use with caution in patients with narrow-angle glaucoma as the medication may worsen the condition.
- Monitor patients with urinary retention or benign prostatic hyperplasia.
- Avoid concurrent use of other anticholinergic medications (such as tiotropium, ipratropium, umeclidinium, or glycopyrrolate) due to additive effects.
- Patients should report any signs of immediate hypersensitivity reactions.
Avoid Interactions
- Avoid combining Tudorza Pressair with other anticholinergic medications due to risk of additive anticholinergic effects including urinary retention, constipation, and tachycardia.
- Anticholinergic agents that should not be co-administered include tiotropium, ipratropium, umeclidinium, and glycopyrrolate.
- The drug has minimal CYP450 interactions.
References
Frequently Asked Questions
Tudorza Pressair (aclidinium bromide) is a maintenance bronchodilator for chronic obstructive pulmonary disease (COPD) in adults. It opens airways by blocking acetylcholine receptors, helping you breathe more easily throughout the day. Use it regularly for best results, not for sudden breathing problems.
Tudorza Pressair is a twice-daily inhaler for regular COPD maintenance therapy. Each dose contains aclidinium bromide 400 micrograms. Use it at the same times each day, every 12 hours, even when feeling well. The medication takes approximately 30 minutes to reach peak effect.
Tudorza Pressair commonly causes headache (occurring in about 7% of patients) and upper respiratory tract infection symptoms including nasopharyngitis. Some patients experience cough or diarrhea. Most effects are mild. Contact your doctor if you develop sudden severe breathing problems, eye pain, or difficulty urinating.
Do not combine Tudorza Pressair with other anticholinergic inhalers like tiotropium or ipratropium because of additive effects. Tell your doctor about all inhaled medications and other COPD treatments you take. Inform your healthcare provider if you have narrow-angle glaucoma or urinary problems.
No, Tudorza Pressair is only for regular maintenance of COPD and cannot treat sudden breathing problems. If you experience acute severe breathlessness, use a fast-acting rescue inhaler such as albuterol and seek immediate medical help. Contact emergency services if your symptoms worsen rapidly.
The safety of Tudorza Pressair during pregnancy is not well-established in studies. If you are pregnant or planning pregnancy, discuss this medication with your healthcare provider before starting or continuing use. They can help assess the risks versus benefits for managing your COPD during pregnancy.

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