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Ventolin 100mcg/dose Inhaler
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Indications & Clinical Uses
- Ventolin 100mcg/dose is the UK Ventolin Evohaler, a pressurised metered-dose inhaler containing salbutamol (albuterol in US terminology) as salbutamol sulfate, a short-acting beta-2 agonist bronchodilator, with 200 actuations per canister.
- It relieves and prevents bronchospasm in reversible airway obstruction such as asthma, and can be used before exercise or allergen exposure.
- The UK SmPC lists adults, adolescents and children aged 4 to 11 years.
- Relief starts within about 5 minutes and lasts 4 to 6 hours.
- It is a reliever inhaler, not a replacement for regular anti-inflammatory treatment.
- Do not confuse it with the US Ventolin HFA, which delivers 90 mcg albuterol per actuation, or with Ventolin Nebules and syrup, which are different products and strengths.
Side Effects
- Common side effects are tremor, headache and a fast heartbeat (tachycardia).
- Uncommon effects include palpitations, mouth or throat irritation and muscle cramps.
- Rare effects include low potassium (hypokalaemia) and widening of peripheral blood vessels.
- Very rare effects include allergic reactions, hyperactivity, heart rhythm problems, myocardial ischaemia and paradoxical bronchospasm, where wheezing gets worse straight after a dose.
- Stop the inhaler and seek urgent help if breathing worsens after using it.
- The SmPC does not carry a boxed warning.
- Seek medical advice if your relief does not last as long or you need it more often.
Precautions & Warnings
- Contraindicated with hypersensitivity to salbutamol or any ingredient.
- Potentially serious low potassium can result from beta-2 agonist therapy, and xanthines, steroids and diuretics can add to this.
- Use with care if you have severe heart disease, an overactive thyroid or diabetes.
- Regular anti-inflammatory treatment should continue even when symptoms settle.
- The SmPC's maximum on-demand use is 8 inhalations in 24 hours; needing more is a sign to get medical advice.
- Use in pregnancy and breastfeeding is not recommended unless clearly necessary, as animal studies showed teratogenicity and salbutamol probably passes into breast milk.
- No effect on driving is reported.
- Store below 30°C away from frost and direct sunlight, and never puncture or burn the canister, even when empty.
Avoid Interactions
- Medicines that increase risk: xanthines, steroids and diuretics can add to low potassium; caution is needed.
- Medicines that reduce efficacy: non-selective beta-blockers such as propranolol should not normally be prescribed with salbutamol, as they block its effect and may provoke bronchospasm.
- Tell your prescriber and pharmacist about all prescription medicines, non-prescription products and supplements you take.
- The labels reviewed do not list foods or alcohol interactions.
- Tell your prescriber if you take any of the medicines above so that your potassium and heart rate can be considered.
- Do not start or stop any medicine without checking with your healthcare provider.
References
Frequently Asked Questions
Ventolin Evohaler (salbutamol, called albuterol in the US) is a reliever inhaler that opens the airways to relieve and prevent bronchospasm in asthma and other reversible airway obstruction. It is suitable for adults, adolescents and children aged 4 to 11. Relief starts within about 5 minutes and lasts 4 to 6 hours.
Use Ventolin 100 mcg as 1 to 2 puffs for symptoms, or 2 puffs 10 to 15 minutes before exercise or allergen exposure. The maximum on-demand use is 8 puffs in 24 hours. Regular use is up to 4 times daily as prescribed. Follow your prescriber's instructions.
Common Ventolin side effects are tremor, headache and a fast heartbeat. Rarer effects include palpitations, muscle cramps, low potassium and, very rarely, paradoxical bronchospasm, where wheezing worsens straight after a dose. Get urgent help if breathing gets worse after using the inhaler.
Avoid non-selective beta-blockers such as propranolol, which can block salbutamol and trigger bronchospasm. Take extra care with xanthines, steroids and diuretics, which can lower potassium further. Do not puncture or burn the canister, even when it is empty, and do not store it above 30°C.
Store Ventolin Evohaler (salbutamol) below 30°C and protect it from frost and direct sunlight. Do not expose the canister to temperatures above 50°C. Never puncture, break or burn it, even when empty. This applies to the 100 microgram, 200-dose inhaler; check your leaflet if you use a different Ventolin product.
The UK label says Ventolin (salbutamol) is not recommended in pregnancy unless clearly necessary, as animal studies showed teratogenic effects. Salbutamol probably passes into breast milk, so use only if benefit outweighs risk to the baby. Talk to your healthcare provider before using it if pregnant or breastfeeding.
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